Pathos AI : NYC (hybrid, 3-4 days onsite)

chrisposhka5/5/26Less than 1 minute

Pathos AI - Senior Software / AI Engineer - NYC (hybrid, 3-4 days onsite) - Full-time - $180-200K + equity - VISA

Pathos is an oncology biotech building AI as the operating system for drug development. We have:

200+ petabytes of multimodal patient data linked to outcomes
The largest foundation model in oncology (in development)
Backing to build a generational company
Founded by Eric Lefkofsky (Tempus) and Ryan Fukushima Learn more: https://pathos.com

This role is 0→1 product work. You'll build:

AI agents and copilots for internal teams (BD, clinical, computational biology, lab)
MCP-style servers so agents can safely interact with internal systems
Data pipelines into a governed warehouse / knowledge graph

Looking for senior software/ML engineers who:

Have 4+ years shipping user-facing systems
Are fluent in Python + TypeScript/JavaScript, comfortable full-stack
Have built LLM-powered workflows (OpenAI API or similar)
Have production experience with APIs, eventing, data engineering (GCP/BigQuery a plus)
Bonus: prior agent/retrieval/ML infra work, or experience in regulated clinical environments

Hybrid in NYC (3-4 days onsite). $180-200K base + equity (3-yr vest, no liquidity until exit). Visa support available.

Apply: email chris.poshka+hn@pathos.com.

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